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Africa still at risk of yellow fever – WHO report Featured

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The World Health Organisation, WHO, has released its global report on the outbreak of Yellow Fever. For Africa, it was not good news as Angola, Democratic Republic of The Congo, Ghana, Chad, Guinea and Uganda remained at risk.

WHO, in the report dated July 8, listed Angola as with the highest record of suspected cases put at 3552 while DRC has suspected cases at 1307.

The global health watchdog gave an in-depth report of its team’s findings country-by-country.

Yellow fever outbreak was detected in Luanda, Angola late in December 2015. The first cases were confirmed by the National Institute for Communicable Diseases (NICD) in South Africa on 19 January 2016 and by the Institut Pasteur Dakar (IP-D) on 20 January. Subsequently, a rapid increase in the number of cases has been observed.

In its summarised report, WHO said that in Angola, as of 1 July 2016 a total of 3552 suspected cases have been reported, of which 875 are confirmed. The total number of reported deaths is 355, of which 117 were reported among confirmed cases. Suspected cases have been reported in all 18 provinces and confirmed cases have been reported in 16 of 18 provinces and 80 of 125 reporting districts.

“Mass vaccination campaigns first began in Luanda and have now expanded to cover most of the other affected parts of Angola. Recently, the campaigns have focused on border areas. Despite extensive vaccination efforts circulation of the virus persists” the UN agency reported.

Eleven reactive and pre-emptive mass vaccination campaigns are ongoing in several districts in Benguela, Huambo, Huila, Kwanza Norte, Kwanza Sul, Lunda Norte and Uige provinces, according to WHO. Six other mass vaccination campaigns are nearing completion. Mop-up campaigns are being implemented in parts of the provinces of Cunene, Lunda Norte, Uige and Zaire.

There is little to cheer in DRC as WHO noted that there are no updates regarding the epidemiological situation in the Democratic Republic of The Congo (DRC).

It however, observed that According to the latest available information (as of 24 June), the total number of notified suspected cases is 1307, with 68 confirmed cases and 75 reported deaths. Cases have been reported in 22 health zones in five of 26 provinces. Of the 68 confirmed cases, 59 were imported from Angola, two are sylvatic (not related to the outbreak) and seven are autochthonous.

In DRC, surveillance efforts have increased and vaccination campaigns have centred on affected health zones in Kinshasa and Kongo Central.

WHO observed that risks for fresh outbreak across the continent exist. Two additional countries have reported confirmed yellow fever cases imported from Angola: Kenya (two cases) and People’s Republic of China (11 cases). These cases highlight the risk of international spread through non-immunised travellers.

Seven countries (Brazil, Chad, Colombia, Ghana, Guinea, Peru and Uganda) are currently reporting yellow fever outbreaks or sporadic cases not linked to the Angolan outbreak.

WHO Strategic Advisory Group of Experts (SAGE) on Immunization reviewed existing evidence that demonstrates that using a fifth of a standard vaccine dose would still provide protection against the disease for at least 12 months and possibly longer. This approach, known as fractional dosing, is under consideration as a short-term measure, in the context of a potential vaccine shortage in emergencies.

WHO further noted that the outbreak in Angola remains of high concern due to certain factors that include persistent local transmission despite the fact that approximately 15 million people have been vaccinated; local transmission has been reported in 12 highly populated provinces including Luanda.

It continued: The continued extension of the outbreak to new provinces and new districts; high risk of spread to neighbouring countries. As the borders are porous with substantial cross-border social and economic activities, further transmission cannot be excluded. Viraemic travelling patients pose a risk for the establishment of local transmission especially in countries where adequate vectors and susceptible human populations are present; risk of establishment of local transmission in other provinces where no autochthonous cases are reported; and high index of suspicion of ongoing transmission in hard-to-reach areas like Cabinda.

In DRC, the outbreak has spread to three provinces. Given the limited availability of vaccines, the large Angolan community in Kinshasa, the porous border between Angola and DRC, and the presence and the activity of the vector Aedes in the country, the outbreak might extend to other provinces, in particular Kasai, Kasai Central and Lualaba.

The virus in Angola and DRC is largely concentrated in main cities; however, there is a high risk of spread and local transmission to other provinces in both countries. In addition, the risk is high for potential spread to bordering countries, especially those classified as low-risk (i.e. Namibia, Zambia) and where the population, travellers and foreign workers are not vaccinated for yellow fever.

As part of its early warning and recommendation, WHO noted that some African countries - Chad, Ghana, Guinea, Republic of Congo and Uganda - and some countries in South America (Brazil, Colombia and Peru) have reported cases of yellow fever in 2016. “These events are not related to the Angolan outbreak, but there remains a need for vaccines in those countries, which poses additional strain on the limited global yellow fever vaccine stockpile”, it stated.

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